HYBRID EVENT: You can participate in person at Singapore or Virtually from your home or work.

5th Edition of

International Public Health Conference

March 19-21, 2026 | Singapore

Epigenetics

Epigenetics

Epigenetics is the study of heritable changes in gene function that do not involve alterations to the underlying DNA sequence. It explores how environmental factors and experiences can influence gene expression, impacting an individual's traits and health outcomes. Unlike genetic mutations, epigenetic modifications can be reversible, making them dynamic contributors to an organism's phenotype. Epigenetic mechanisms include DNA methylation, histone modification, and non-coding RNA molecules, all of which regulate gene activity. These modifications can be influenced by factors such as diet, stress, toxins, and lifestyle choices, leading to the concept of "epigenetic marks" that shape an individual's susceptibility to diseases. Research in epigenetics has revealed its role in various conditions, including cancer, neurological disorders, and cardiovascular diseases. It has also shed light on the intergenerational transmission of traits, showing how experiences of one generation can influence the epigenetic landscape of the next. Epigenetics challenges the traditional nature versus nurture debate by highlighting the intricate interplay between genetics and the environment. Understanding these epigenetic processes holds promise for personalized medicine, as interventions targeting specific epigenetic modifications may provide novel therapeutic strategies. In summary, epigenetics provides a fascinating insight into the molecular mechanisms that bridge genetic information and environmental influences, shaping the complexity of life and health outcomes across generations.

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