Title : An indigenous monkeypox (mpox) case in a non-endemic region: A case report
Abstract:
Background: Mpox, a zoonotic viral infection caused by the Monkeypox virus, has recently emerged as a global public health concern. Although it is primarily endemic to certain regions, cases are increasingly being reported in non-endemic areas, presenting unique diagnostic and clinical challenges. In this manuscript, we report an indigenous case of Mpox in a non-endemic region with unusual clinical presentation.
Case presentation: A 32-year-old female, residing in District Khyber, presented with a 4-day history of fever, fatigue, myalgia, sore throat, body rashes, oral and nasopharyngeal lesions, and widespread vesiculopustular eruptions. She was diagnosed with monkeypox on February 21, 2025. Her husband recently returned from Saudi Arabia, and was suspected to be the primary source of infection. The patient had no history of animal contact, recent vaccination or immunocompromising conditions.
Managing and Outcome: The patient was isolated at THQ hospital Dogra, and a multidisciplinary public health response was initiated. The patient received supportive treatment, including antipyretics, analgesics, and fluid management. Infection prevention and control measures were taken, and contact tracing of household members and school-going children was initiated. The patient showed gradual improvement and complete resolution of symptoms in three weeks.
Conclusion: Indigenous cases Mpox are an emerging challenge. Early identification, accurate diagnosis, and supportive care are crucial to reduce mortality and prevent outbreaks. In this case report, we highlight the risk of Mpox transmission among local masses through international travel and underscore the need for enhanced surveillance and screening at airports.
