Therapeutic potential of diet and exercise in the treatment of obese and lean young women with polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age. The symptoms of PCOS include but are not limited to irregular menses, biochemical and/or clinical hyperandrogenism, polycystic ovaries on ultrasound. PCOS is also characterized by insulin resistance, especially in obese women. And the majority of women with PCOS are either overweight or obese. However, lean women and adolescent girls may also be affected by PCOS. Considering the rise in childhood obesity, PCOS and its metabolic and reproductive consequences represent a public health challenge. The focus of the presentation will be related to current research findings. These findings suggests a therapeutic potential of lifestyle modification on improved hormonal and metabolic profile, and reduced inflammation and oxidative stress, both in obese and lean young women with PCOS.